SNX6

GENE INFORMATION

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Gene name

SNX6

Synonyms

Description

Sorting nexin 6 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q13.1

Chromosome location (bp)

34561094 - 34630183

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000129515 (version 78.38)

Entrez gene

58533

UniProt

Q9UNH7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UNH7

Antibodypedia

SNX6 antibodies
 

PROTEIN VIEW

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SNX6-001
 
SNX6-002
 
SNX6-005
 
SNX6-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SNX6-001 ENSP00000379779
ENST00000396526
Q9UNH7
Show all »
Show » Show » 290 33.6 No 0
SNX6-002 ENSP00000355217
ENST00000362031
Q5QTQ6
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Show » Show » 418 47.8 No 0
SNX6-005 ENSP00000452577
ENST00000557265
G3V5X9
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Show » Show » 239 27 No 0
SNX6-009 ENSP00000452520
ENST00000555648
G3V5U2
Show all »
Show » Show » 132 15.1 No 0