COX4I2

GENE INFORMATION

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Gene name

COX4I2 (HGNC Symbol)

Synonyms

COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2

Description

Cytochrome c oxidase subunit IV isoform 2 (lung) (HGNC Symbol)

Entrez gene summary

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q11.21

Chromosome location (bp)

31637888 - 31645006

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000131055 (version 78.38)

Entrez gene

84701

UniProt

Q96KJ9 (UniProt - Evidence at protein level)

neXtProt

NX_Q96KJ9

Antibodypedia

COX4I2 antibodies
 

PROTEIN VIEW

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COX4I2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COX4I2-001 ENSP00000365243
ENST00000376075
Q96KJ9
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