EMR3

GENE INFORMATION

? »

Gene name

EMR3

Synonyms

Description

Egf-like module containing, mucin-like, hormone receptor-like 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]

Chromosome

19

Cytoband

p13.12

Chromosome location (bp)

14619117 - 14690027

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000131355 (version 78.38)

Entrez gene

84658

UniProt

Q9BY15 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9BY15

Antibodypedia

EMR3 antibodies
 

PROTEIN VIEW

? »
 
 
 
EMR3-001
 
EMR3-002
 
EMR3-003
 
EMR3-004
 
EMR3-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EMR3-001 ENSP00000253673
ENST00000253673
Q9BY15
Show all »
Show » Show » 652 72.6 Yes 7
EMR3-002 ENSP00000396208
ENST00000443157
E7EW83
Show all »
Show » Show » 526 58.4 Yes 7
EMR3-003 ENSP00000471853
ENST00000599900
M0R1G2
Show all »
Show » Show » 437 48.8 No 7
EMR3-004 ENSP00000469965
ENST00000595472
M0QYN7
Show all »
Show » 57 6.1 Yes 0
EMR3-201 ENSP00000340758
ENST00000344373
Q9BY15
Show all »
Show » Show » 600 66.8 Yes 7