MRPS25

GENE INFORMATION

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Gene name

MRPS25 (HGNC Symbol)

Synonyms

DKFZp313H0817, FLJ00023, MRP-S25, RPMS25

Description

Mitochondrial ribosomal protein S25 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 4. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

p25.1

Chromosome location (bp)

15042460 - 15065335

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000131368 (version 78.38)

Entrez gene

64432

UniProt

P82663 (UniProt - Evidence at protein level)

neXtProt

NX_P82663

Antibodypedia

MRPS25 antibodies
 

PROTEIN VIEW

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MRPS25-001
 
MRPS25-002
 
MRPS25-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS25-001 ENSP00000253686
ENST00000253686
P82663
Show all »
Show » Show » 173 20.1 No 0
MRPS25-002 ENSP00000407733
ENST00000444840
P82663
Show all »
Show » Show » 129 15 No 0
MRPS25-003 ENSP00000390882
ENST00000449354
P82663
Show all »
Show » Show » 145 16.6 No 0