SERPINF1

GENE INFORMATION

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Gene name

SERPINF1 (HGNC Symbol)

Synonyms

EPC-1, PEDF, PIG35

Description

Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.[provided by RefSeq, Mar 2011]

Chromosome

17

Cytoband

p13.3

Chromosome location (bp)

1761959 - 1777574

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000132386 (version 78.38)

Entrez gene

5176

UniProt

P36955 (UniProt - Evidence at protein level)

neXtProt

NX_P36955

Antibodypedia

SERPINF1 antibodies
 

PROTEIN VIEW

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SERPINF1-001
 
SERPINF1-003
 
SERPINF1-004
 
SERPINF1-009
 
SERPINF1-010
 
SERPINF1-011
 
SERPINF1-012
 
SERPINF1-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SERPINF1-001 ENSP00000254722
ENST00000254722
P36955
Show all »
Show » Show » 418 46.3 Yes 0
SERPINF1-003 ENSP00000459869
ENST00000570731
I3L2R7
Show all »
Show » 132 14 Yes 0
SERPINF1-004 ENSP00000460842
ENST00000577053
I3L3Z3
Show all »
Show » 111 11.8 Yes 0
SERPINF1-009 ENSP00000461214
ENST00000576406
I3L4F9
Show all »
Show » 91 10.3 No 0
SERPINF1-010 ENSP00000461660
ENST00000571360
I3L4Z0
Show all »
Show » Show » 128 13.8 Yes 0
SERPINF1-011 ENSP00000460905
ENST00000571149
I3L425
Show all »
Show » 87 9.1 Yes 0
SERPINF1-012 ENSP00000461405
ENST00000573763
I3L4N7
Show all »
Show » Show » 138 15.9 No 0
SERPINF1-013 ENSP00000458484
ENST00000572048
I3L107
Show all »
Show » 99 11.2 No 0