FCRL2

GENE INFORMATION

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Gene name

FCRL2 (HGNC Symbol)

Synonyms

CD307b, FCRH2, IRTA4, SPAP1

Description

Fc receptor-like 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Apr 2009]

Chromosome

1

Cytoband

q23.1

Chromosome location (bp)

157745733 - 157777132

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000132704 (version 78.38)

Entrez gene

79368

UniProt

Q96LA5 (UniProt - Evidence at protein level)

neXtProt

NX_Q96LA5

Antibodypedia

FCRL2 antibodies
 

PROTEIN VIEW

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FCRL2-001
 
FCRL2-003
 
FCRL2-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FCRL2-001 ENSP00000355157
ENST00000361516
Q96LA5
Show all »
Show » Show » 508 55.5 Yes 1
FCRL2-003 ENSP00000417393
ENST00000469986
Q96LA5
Show all »
Show » Show » 192 20.7 No 1
FCRL2-004 ENSP00000357163
ENST00000368181
Q96LA5
Show all »
Show » Show » 202 22.5 Yes 1