MYH8

GENE INFORMATION

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Gene name

MYH8 (HGNC Symbol)

Synonyms

MyHC-peri, MyHC-pn

Description

Myosin, heavy chain 8, skeletal muscle, perinatal (HGNC Symbol)

Entrez gene summary

Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome. [provided by RefSeq, Sep 2009]

Chromosome

17

Cytoband

p13.1

Chromosome location (bp)

10390322 - 10421950

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000133020 (version 78.38)

Entrez gene

4626

UniProt

P13535 (UniProt - Evidence at protein level)

neXtProt

NX_P13535

Antibodypedia

MYH8 antibodies
 

PROTEIN VIEW

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MYH8-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MYH8-001 ENSP00000384330
ENST00000403437
P13535
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