PRAM1

GENE INFORMATION

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Gene name

PRAM1 (HGNC Symbol)

Synonyms

PML-RAR

Description

PML-RARA regulated adaptor molecule 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha). [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.2

Chromosome location (bp)

8490056 - 8503112

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000133246 (version 78.38)

Entrez gene

84106

UniProt

neXtProt

Antibodypedia

PRAM1 antibodies
 

PROTEIN VIEW

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PRAM1-001
 
PRAM1-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRAM1-001 ENSP00000408342
ENST00000423345
Show » Show » 670 74 No 0
PRAM1-004 ENSP00000471634
ENST00000600262
M0R149
Show all »
Show » 180 19.7 No 0