ROCK2

GENE INFORMATION

? »

Gene name

ROCK2

Synonyms

Description

Rho-associated, coiled-coil containing protein kinase 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

p25.1

Chromosome location (bp)

11179761 - 11348330

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134318 (version 78.38)

Entrez gene

9475

UniProt

O75116 (UniProt - Evidence at protein level)

neXtProt

NX_O75116

Antibodypedia

ROCK2 antibodies
 

PROTEIN VIEW

? »
 
 
 
ROCK2-001
 
ROCK2-006
 
ROCK2-007
 
ROCK2-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ROCK2-001 ENSP00000317985
ENST00000315872
O75116
Show all »
Show » Show » 1388 160.9 No 0
ROCK2-006 ENSP00000385509
ENST00000401753
E9PF63
Show all »
Show » Show » 1145 133.3 No 0
ROCK2-007 ENSP00000395957
ENST00000431087
C9JFJ0
Show all »
Show » Show » 203 23.2 No 0
ROCK2-201 ENSP00000481789
ENST00000616279
Q14DU5
Show all »
Show » Show » 703 82.1 No 0