CLDN10

GENE INFORMATION

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Gene name

CLDN10 (HGNC Symbol)

Synonyms

CPETRL3, OSP-L

Description

Claudin 10 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010]

Chromosome

13

Cytoband

q32.1

Chromosome location (bp)

95433604 - 95579759

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134873 (version 78.38)

Entrez gene

9071

UniProt

P78369 (UniProt - Evidence at protein level)

neXtProt

NX_P78369

Antibodypedia

CLDN10 antibodies
 

PROTEIN VIEW

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CLDN10-001
 
CLDN10-002
 
CLDN10-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLDN10-001 ENSP00000366069
ENST00000376873
P78369
Show all »
Show » Show » 226 24.3 No 3
CLDN10-002 ENSP00000299339
ENST00000299339
P78369
Show all »
Show » Show » 228 24.5 No 3
CLDN10-003 ENSP00000366051
ENST00000376855
Q5W075
Show all »
Show » Show » 73 7.7 No 1