TPP2

GENE INFORMATION

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Gene name

TPP2

Synonyms

Description

Tripeptidyl peptidase II (HGNC Symbol)

Entrez gene summary

This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class. [provided by RefSeq, Jul 2008]

Chromosome

13

Cytoband

q33.1

Chromosome location (bp)

102597003 - 102679958

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134900 (version 78.38)

Entrez gene

7174

UniProt

P29144 (UniProt - Evidence at protein level)

neXtProt

NX_P29144

Antibodypedia

TPP2 antibodies
 

PROTEIN VIEW

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TPP2-001
 
TPP2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TPP2-001 ENSP00000365233
ENST00000376065
P29144
Show all »
Show » Show » 1249 138.3 No 0
TPP2-002 ENSP00000365220
ENST00000376052
Q5VZU9
Show all »
Show » Show » 1262 139.8 No 0