HRK

GENE INFORMATION

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Gene name

HRK (HGNC Symbol)

Synonyms

DP5

Description

Harakiri, BCL2 interacting protein (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]

Chromosome

12

Cytoband

q24.22

Chromosome location (bp)

116856144 - 116881441

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135116 (version 78.38)

Entrez gene

8739

UniProt

O00198 (UniProt - Evidence at protein level)

neXtProt

NX_O00198

Antibodypedia

HRK antibodies
 

PROTEIN VIEW

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HRK-001
 
HRK-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HRK-001 ENSP00000257572
ENST00000257572
O00198
Show all »
Show » Show » 91 9.9 No 1
HRK-002 ENSP00000465379
ENST00000550505
Show » 18 1.9 No 0