NT5E

GENE INFORMATION

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Gene name

NT5E (HGNC Symbol)

Synonyms

CALJA, CD73, eN, eNT, NT5

Description

5'-nucleotidase, ecto (CD73) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]

Chromosome

6

Cytoband

q14.3

Chromosome location (bp)

85449584 - 85495791

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135318 (version 78.38)

Entrez gene

4907

UniProt

P21589 (UniProt - Evidence at protein level)

neXtProt

NX_P21589

Antibodypedia

NT5E antibodies
 

PROTEIN VIEW

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NT5E-001
 
NT5E-002
 
NT5E-003
 
NT5E-004
 
NT5E-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NT5E-001 ENSP00000257770
ENST00000257770
P21589
Show all »
Show » Show » 574 63.4 Yes 1
NT5E-002 ENSP00000358660
ENST00000369646
Q96B60
Show all »
Show » Show » 264 28.8 Yes 0
NT5E-003 ENSP00000414674
ENST00000416334
Show » Show » 230 25.6 No 0
NT5E-004 ENSP00000387630
ENST00000437581
Show » Show » 179 20.2 No 0
NT5E-201 ENSP00000358665
ENST00000369651
P21589
Show all »
Show » Show » 524 57.9 Yes 1