CD63

GENE INFORMATION

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Gene name

CD63 (HGNC Symbol)

Synonyms

ME491, MLA1, TSPAN30

Description

CD63 molecule (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]

Chromosome

12

Cytoband

q13.2

Chromosome location (bp)

55725323 - 55729707

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135404 (version 78.38)

Entrez gene

967

UniProt

P08962 (UniProt - Evidence at protein level)

neXtProt

NX_P08962

Antibodypedia

CD63 antibodies
 

PROTEIN VIEW

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 « 
 
CD63-001
 
CD63-002
 
CD63-003
 
CD63-004
 
CD63-006
 
CD63-007
 
CD63-008
 
CD63-009
 
CD63-010
 
CD63-011
 
CD63-012
 
CD63-014
 
CD63-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD63-001 ENSP00000447730
ENST00000549117
P08962
Show all »
Show » Show » 238 25.6 No 4
CD63-002 ENSP00000257857
ENST00000257857
P08962
Show all »
Show » Show » 238 25.6 No 4
CD63-003 ENSP00000449337
ENST00000552692
P08962
Show all »
Show » Show » 238 25.6 No 4
CD63-004 ENSP00000446807
ENST00000552754
P08962
Show all »
Show » Show » 215 23.4 No 3
CD63-006 ENSP00000450191
ENST00000546457
F8VNT9
Show all »
Show » Show » 133 14.3 No 3
CD63-007 ENSP00000449281
ENST00000552164
F8VWK8
Show all »
Show » Show » 217 23.4 No 3
CD63-008 ENSP00000446752
ENST00000551173
F8W022
Show all »
Show » Show » 215 23.1 No 3
CD63-009 ENSP00000447356
ENST00000546939
P08962
Show all »
Show » Show » 156 17.3 Yes 1
CD63-010 ENSP00000448091
ENST00000550776
P08962
Show all »
Show » Show » 156 17.3 Yes 1
CD63-011 ENSP00000447938
ENST00000548898
F8VV56
Show all »
Show » Show » 145 16 No 1
CD63-012 ENSP00000449684
ENST00000552067
F8VV56
Show all »
Show » Show » 145 16 No 1
CD63-014 ENSP00000449654
ENST00000548160
F8VV56
Show all »
Show » Show » 145 16 No 1
CD63-201 ENSP00000393502
ENST00000420846
P08962
Show all »
Show » Show » 238 25.6 No 4