USP15

GENE INFORMATION

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Gene name

USP15 (HGNC Symbol)

Synonyms

KIAA0529, UNPH4

Description

Ubiquitin specific peptidase 15 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011]

Chromosome

12

Cytoband

q14.1

Chromosome location (bp)

62260338 - 62417431

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135655 (version 78.38)

Entrez gene

9958

UniProt

Q9Y4E8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y4E8

Antibodypedia

USP15 antibodies
 

PROTEIN VIEW

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USP15-001
 
USP15-002
 
USP15-003
 
USP15-006
 
USP15-011
 
USP15-014
 
USP15-017
 
USP15-019
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

USP15-001 ENSP00000258123
ENST00000353364
Q9Y4E8
Show all »
Show » Show » 952 109.3 No 0
USP15-002 ENSP00000280377
ENST00000280377
Q9Y4E8
Show all »
Show » Show » 981 112.4 No 0
USP15-003 ENSP00000309240
ENST00000312635
Q9Y4E8
Show all »
Show » Show » 235 27.1 No 0
USP15-006 ENSP00000448372
ENST00000549415
H0YI26
Show all »
Show » Show » 157 18.2 No 0
USP15-011 ENSP00000448393
ENST00000549237
F8VZG8
Show all »
Show » Show » 240 27.6 No 0
USP15-014 ENSP00000446843
ENST00000548836
F8VZG8
Show all »
Show » Show » 140 16.2 No 0
USP15-017 ENSP00000449563
ENST00000546694
F8VVY7
Show all »
Show » 106 12.3 No 0
USP15-019 ENSP00000447603
ENST00000549523
F8W0H4
Show all »
Show » Show » 175 20.1 No 0