DRAM1

GENE INFORMATION

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Gene name

DRAM1 (HGNC Symbol)

Synonyms

DRAM, FLJ11259

Description

DNA-damage regulated autophagy modulator 1 (HGNC Symbol)

Entrez gene summary

This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q23.2

Chromosome location (bp)

101877351 - 102012130

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136048 (version 78.38)

Entrez gene

55332

UniProt

Q8N682 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N682

Antibodypedia

DRAM1 antibodies
 

PROTEIN VIEW

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DRAM1-001
 
DRAM1-002
 
DRAM1-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DRAM1-001 ENSP00000258534
ENST00000258534
Q8N682
Show all »
Show » Show » 238 26.3 No 6
DRAM1-002 ENSP00000445827
ENST00000544152
B7Z4T0
Show all »
Show » 128 14 No 3
DRAM1-006 ENSP00000447906
ENST00000549066
Show » 53 5.9 No 0