STAM

GENE INFORMATION

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Gene name

STAM (HGNC Symbol)

Synonyms

STAM1

Description

Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

Chromosome

10

Cytoband

p12.33

Chromosome location (bp)

17644125 - 17715914

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136738 (version 78.38)

Entrez gene

8027

UniProt

Q92783 (UniProt - Evidence at protein level)

neXtProt

NX_Q92783

Antibodypedia

STAM antibodies
 

PROTEIN VIEW

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STAM-001
 
STAM-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

STAM-001 ENSP00000366746
ENST00000377524
Q92783
Show all »
Show » Show » 540 59.2 No 0
STAM-003 ENSP00000366721
ENST00000377500
A6NMU3
Show all »
Show » Show » 173 19.2 No 0