XPA

GENE INFORMATION

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Gene name

XPA (HGNC Symbol)

Synonyms

XP1, XPAC

Description

Xeroderma pigmentosum, complementation group A (HGNC Symbol)

Entrez gene summary

This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]

Chromosome

9

Cytoband

q22.33

Chromosome location (bp)

97674909 - 97697357

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136936 (version 78.38)

Entrez gene

7507

UniProt

P23025 (UniProt - Evidence at protein level)

neXtProt

NX_P23025

Antibodypedia

XPA antibodies
 

PROTEIN VIEW

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XPA-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

XPA-001 ENSP00000364270
ENST00000375128
P23025
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