POU2F3

GENE INFORMATION

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Gene name

POU2F3 (HGNC Symbol)

Synonyms

Epoc-1, OCT11, PLA-1, Skn-1a

Description

POU class 2 homeobox 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Chromosome

11

Cytoband

q23.3

Chromosome location (bp)

120236640 - 120319944

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137709 (version 78.38)

Entrez gene

25833

UniProt

Q9UKI9 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9UKI9

Antibodypedia

POU2F3 antibodies
 

PROTEIN VIEW

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POU2F3-001
 
POU2F3-005
 
POU2F3-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

POU2F3-001 ENSP00000441687
ENST00000543440
Q9UKI9
Show all »
Show » Show » 436 47.4 No 0
POU2F3-005 ENSP00000453150
ENST00000532663
H0YLC5
Show all »
Show » Show » 161 17 No 0
POU2F3-006 ENSP00000260264
ENST00000260264
Q9UKI9
Show all »
Show » Show » 438 47.6 No 0