KLRG1

GENE INFORMATION

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Gene name

KLRG1 (HGNC Symbol)

Synonyms

2F1, CLEC15A, MAFA, MAFA-L

Description

Killer cell lectin-like receptor subfamily G, member 1 (HGNC Symbol)

Entrez gene summary

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. Alternatively spliced transcript variants have been reported, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

p13.31

Chromosome location (bp)

8950044 - 9010760

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000139187 (version 78.38)

Entrez gene

10219

UniProt

Q96E93 (UniProt - Evidence at protein level)

neXtProt

NX_Q96E93

Antibodypedia

KLRG1 antibodies
 

PROTEIN VIEW

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KLRG1-001
 
KLRG1-002
 
KLRG1-004
 
KLRG1-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLRG1-001 ENSP00000349477
ENST00000356986
Q96E93
Show all »
Show » Show » 189 21.2 No 1
KLRG1-002 ENSP00000266551
ENST00000266551
Q96E93
Show all »
Show » Show » 195 21.8 No 1
KLRG1-004 ENSP00000445627
ENST00000539240
F5H207
Show all »
Show » Show » 81 9.5 No 0
KLRG1-006 ENSP00000443658
ENST00000543895
F5H8E3
Show all »
Show » Show » 80 9.4 No 0