VAMP1

GENE INFORMATION

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Gene name

VAMP1 (HGNC Symbol)

Synonyms

SYB1, VAMP-1

Description

Vesicle-associated membrane protein 1 (synaptobrevin 1) (HGNC Symbol)

Entrez gene summary

Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014]

Chromosome

12

Cytoband

p13.31

Chromosome location (bp)

6462237 - 6470987

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000139190 (version 78.38)

Entrez gene

6843

UniProt

P23763 (UniProt - Evidence at protein level)

neXtProt

NX_P23763

Antibodypedia

VAMP1 antibodies
 

PROTEIN VIEW

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VAMP1-001
 
VAMP1-002
 
VAMP1-003
 
VAMP1-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VAMP1-001 ENSP00000355122
ENST00000361716
P23763
Show all »
Show » Show » 117 12.8 No 1
VAMP1-002 ENSP00000379602
ENST00000396308
P23763
Show all »
Show » Show » 118 12.9 No 1
VAMP1-003 ENSP00000383702
ENST00000400911
P23763
Show all »
Show » Show » 116 12.7 No 1
VAMP1-011 ENSP00000444181
ENST00000535180
F5GZV7
Show all »
Show » Show » 116 12.6 No 1