SERPINA10

GENE INFORMATION

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Gene name

SERPINA10 (HGNC Symbol)

Synonyms

PZI, ZPI

Description

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2010]

Chromosome

14

Cytoband

q32.13

Chromosome location (bp)

94280455 - 94293271

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000140093 (version 78.38)

Entrez gene

51156

UniProt

Q9UK55 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UK55

Antibodypedia

SERPINA10 antibodies
 

PROTEIN VIEW

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SERPINA10-001
 
SERPINA10-002
 
SERPINA10-003
 
SERPINA10-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SERPINA10-001 ENSP00000261994
ENST00000261994
Q9UK55
Show all »
Show » Show » 444 50.7 Yes 0
SERPINA10-002 ENSP00000450896
ENST00000554723
G3V2W1
Show all »
Show » Show » 484 55.1 No 1
SERPINA10-003 ENSP00000450971
ENST00000554173
Q9UK55
Show all »
Show » Show » 444 50.7 Yes 0
SERPINA10-201 ENSP00000376809
ENST00000393096
Q9UK55
Show all »
Show » Show » 444 50.7 Yes 0