ARHGDIA

GENE INFORMATION

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Gene name

ARHGDIA (HGNC Symbol)

Synonyms

GDIA1, RHOGDI

Description

Rho GDP dissociation inhibitor (GDI) alpha (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Chromosome

17

Cytoband

q25.3

Chromosome location (bp)

81867721 - 81871406

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141522 (version 78.38)

Entrez gene

396

UniProt

P52565 (UniProt - Evidence at protein level)

neXtProt

NX_P52565

Antibodypedia

ARHGDIA antibodies
 

PROTEIN VIEW

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ARHGDIA-001
 
ARHGDIA-002
 
ARHGDIA-006
 
ARHGDIA-009
 
ARHGDIA-012
 
ARHGDIA-013
 
ARHGDIA-015
 
ARHGDIA-016
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARHGDIA-001 ENSP00000269321
ENST00000269321
P52565
Show all »
Show » Show » 204 23.2 No 0
ARHGDIA-002 ENSP00000383556
ENST00000400721
P52565
Show all »
Show » Show » 160 18.2 No 0
ARHGDIA-006 ENSP00000462209
ENST00000583868
J3KRY1
Show all »
Show » Show » 249 27.1 No 0
ARHGDIA-009 ENSP00000463939
ENST00000584461
J3QQX2
Show all »
Show » Show » 235 25.8 No 0
ARHGDIA-012 ENSP00000441348
ENST00000541078
P52565
Show all »
Show » Show » 204 23.2 No 0
ARHGDIA-013 ENSP00000462960
ENST00000579121
J3KTF8
Show all »
Show » Show » 194 21.6 No 0
ARHGDIA-015 ENSP00000464205
ENST00000580685
P52565
Show all »
Show » Show » 204 23.2 No 0
ARHGDIA-016 ENSP00000461956
ENST00000581876
J3KRE2
Show all »
Show » Show » 129 14.8 No 0