EIF4A3

GENE INFORMATION

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Gene name

EIF4A3 (HGNC Symbol)

Synonyms

DDX48, EIF4AIII, KIAA0111

Description

Eukaryotic translation initiation factor 4A3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q25.3

Chromosome location (bp)

80135214 - 80147183

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000141543 (version 78.38)

Entrez gene

9775

UniProt

P38919 (UniProt - Evidence at protein level)

neXtProt

NX_P38919

Antibodypedia

EIF4A3 antibodies
 

PROTEIN VIEW

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EIF4A3-001
 
EIF4A3-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EIF4A3-001 ENSP00000269349
ENST00000269349
P38919
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Show » Show » 411 46.9 No 0
EIF4A3-005 ENSP00000460439
ENST00000576547
I3L3H2
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Show » Show » 125 13.6 No 0