IFNAR1

GENE INFORMATION

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Gene name

IFNAR1 (HGNC Symbol)

Synonyms

IFNAR, IFRC

Description

Interferon (alpha, beta and omega) receptor 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. [provided by RefSeq, Jul 2008]

Chromosome

21

Cytoband

q22.11

Chromosome location (bp)

33324477 - 33359862

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000142166 (version 78.38)

Entrez gene

3454

UniProt

P17181 (UniProt - Evidence at protein level)

neXtProt

NX_P17181

Antibodypedia

IFNAR1 antibodies
 

PROTEIN VIEW

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IFNAR1-001
 
IFNAR1-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IFNAR1-001 ENSP00000270139
ENST00000270139
P17181
Show all »
Show » Show » 557 63.5 Yes 1
IFNAR1-003 ENSP00000400161
ENST00000442071
C9J114
Show all »
Show » Show » 136 15.4 Yes 0