SLC6A3

GENE INFORMATION

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Gene name

SLC6A3 (HGNC Symbol)

Synonyms

DAT, DAT1

Description

Solute carrier family 6 (neurotransmitter transporter), member 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.[provided by RefSeq, Nov 2009]

Chromosome

5

Cytoband

p15.33

Chromosome location (bp)

1392790 - 1445430

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000142319 (version 78.38)

Entrez gene

6531

UniProt

Q01959 (UniProt - Evidence at protein level)

neXtProt

NX_Q01959

Antibodypedia

SLC6A3 antibodies
 

PROTEIN VIEW

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SLC6A3-001
 
SLC6A3-002
 
SLC6A3-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC6A3-001 ENSP00000270349
ENST00000270349
Q01959
Show all »
Show » Show » 620 68.5 No >9
SLC6A3-002 ENSP00000429101
ENST00000513308
H0YBA7
Show all »
Show » Show » 270 29.8 No 5
SLC6A3-003 ENSP00000430324
ENST00000512002
Show » 81 8.9 No 0