PEX14

GENE INFORMATION

? »

Gene name

PEX14

Synonyms

Description

Peroxisomal biogenesis factor 14 (HGNC Symbol)

Entrez gene summary

This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p36.22

Chromosome location (bp)

10472288 - 10630758

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000142655 (version 78.38)

Entrez gene

5195

UniProt

O75381 (UniProt - Evidence at protein level)

neXtProt

NX_O75381

Antibodypedia

PEX14 antibodies
 

PROTEIN VIEW

? »
 
 
 
PEX14-001
 
PEX14-004
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PEX14-001 ENSP00000349016
ENST00000356607
O75381
Show all »
Show » Show » 377 41.2 No 1
PEX14-004 ENSP00000465473
ENST00000491661
K7EK59
Show all »
Show » Show » 160 17.4 No 1