S100A8

GENE INFORMATION

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Gene name

S100A8 (HGNC Symbol)

Synonyms

60B8AG, CAGA, CFAG, CGLA, MRP8, P8

Description

S100 calcium binding protein A8 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

153390032 - 153391188

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000143546 (version 78.38)

Entrez gene

6279

UniProt

P05109 (UniProt - Evidence at protein level)

neXtProt

NX_P05109

Antibodypedia

S100A8 antibodies
 

PROTEIN VIEW

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S100A8-001
 
S100A8-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

S100A8-001 ENSP00000357722
ENST00000368733
P05109
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Show » Show » 93 10.8 No 0
S100A8-002 ENSP00000357721
ENST00000368732
P05109
Show all »
Show » Show » 93 10.8 No 0