NFKBIZ

GENE INFORMATION

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Gene name

NFKBIZ (HGNC Symbol)

Synonyms

FLJ34463, INAP, MAIL

Description

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (HGNC Symbol)

Entrez gene summary

This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q12.3

Chromosome location (bp)

101827991 - 101861022

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000144802 (version 78.38)

Entrez gene

64332

UniProt

Q9BYH8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BYH8

Antibodypedia

NFKBIZ antibodies
 

PROTEIN VIEW

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NFKBIZ-001
 
NFKBIZ-002
 
NFKBIZ-003
 
NFKBIZ-004
 
NFKBIZ-005
 
NFKBIZ-011
 
NFKBIZ-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NFKBIZ-001 ENSP00000377618
ENST00000394054
Q9BYH8
Show all »
Show » Show » 618 68.2 No 0
NFKBIZ-002 ENSP00000325593
ENST00000326151
Q9BYH8
Show all »
Show » Show » 596 64.3 No 0
NFKBIZ-003 ENSP00000325663
ENST00000326172
Q9BYH8
Show all »
Show » Show » 718 78.1 No 0
NFKBIZ-004 ENSP00000419800
ENST00000483180
C9JZ23
Show all »
Show » Show » 601 66.2 No 0
NFKBIZ-005 ENSP00000418502
ENST00000461724
C9J5G8
Show all »
Show » 110 10.9 No 0
NFKBIZ-011 ENSP00000418498
ENST00000491281
C9J5I7
Show all »
Show » 130 14.4 No 0
NFKBIZ-012 ENSP00000420700
ENST00000477601
Show » Show » 130 14.3 No 0