Nuclear receptors
Predicted intracellular proteins
Plasma proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs

GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0001228 [RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription]
GO:0003700 [sequence-specific DNA binding transcription factor activity]
GO:0003707 [steroid hormone receptor activity]
GO:0003713 [transcription coactivator activity]
GO:0004879 [ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0006805 [xenobiotic metabolic process]
GO:0007165 [signal transduction]
GO:0008144 [drug binding]
GO:0008202 [steroid metabolic process]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0010628 [positive regulation of gene expression]
GO:0030522 [intracellular receptor signaling pathway]
GO:0042738 [exogenous drug catabolic process]
GO:0042908 [xenobiotic transport]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046618 [drug export]

GO:0003700 [sequence-specific DNA binding transcription factor activity]
GO:0003707 [steroid hormone receptor activity]
GO:0004887 [thyroid hormone receptor activity]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0030522 [intracellular receptor signaling pathway]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]