MUC4

GENE INFORMATION

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Gene name

MUC4

Synonyms

Description

Mucin 4, cell surface associated (HGNC Symbol)

Entrez gene summary

The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q29

Chromosome location (bp)

195746765 - 195812277

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000145113 (version 78.38)

Entrez gene

4585

UniProt

Q99102 (UniProt - Evidence at protein level)

neXtProt

NX_Q99102

Antibodypedia

MUC4 antibodies
 

PROTEIN VIEW

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MUC4-001
 
MUC4-007
 
MUC4-014
 
MUC4-015
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MUC4-001 ENSP00000417498
ENST00000463781
E9PDY6
Show all »
Show » Show » 5412 542.3 Yes 1
MUC4-007 ENSP00000420243
ENST00000475231
E7ENC5
Show all »
Show » Show » 5360 536.2 Yes 1
MUC4-014 ENSP00000338109
ENST00000349607
Q99102
Show all »
Show » Show » 1125 125.1 Yes 1
MUC4-015 ENSP00000304207
ENST00000346145
Q99102
Show all »
Show » Show » 1176 130.4 Yes 1