G3BP1

GENE INFORMATION

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Gene name

G3BP1 (HGNC Symbol)

Synonyms

G3BP, HDH-VIII

Description

GTPase activating protein (SH3 domain) binding protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q33.1

Chromosome location (bp)

151771045 - 151812785

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000145907 (version 78.38)

Entrez gene

10146

UniProt

Q13283 (UniProt - Evidence at protein level)

neXtProt

NX_Q13283

Antibodypedia

G3BP1 antibodies
 

PROTEIN VIEW

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G3BP1-001
 
G3BP1-002
 
G3BP1-007
 
G3BP1-008
 
G3BP1-009
 
G3BP1-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

G3BP1-001 ENSP00000377681
ENST00000394123
Q13283
Show all »
Show » Show » 466 52.2 No 0
G3BP1-002 ENSP00000348578
ENST00000356245
Q13283
Show all »
Show » Show » 466 52.2 No 0
G3BP1-007 ENSP00000430738
ENST00000523519
E5RIF8
Show all »
Show » Show » 106 12 No 0
G3BP1-008 ENSP00000429920
ENST00000520578
E5RH42
Show all »
Show » Show » 117 13.3 No 0
G3BP1-009 ENSP00000429250
ENST00000507878
E5RIZ6
Show all »
Show » Show » 148 17 No 0
G3BP1-012 ENSP00000428469
ENST00000520006
E5RI46
Show all »
Show » Show » 105 11.8 No 0