SLC17A4

GENE INFORMATION

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Gene name

SLC17A4 (HGNC Symbol)

Synonyms

KIAA2138

Description

Solute carrier family 17, member 4 (HGNC Symbol)

Entrez gene summary

Phosphate homeostasis is maintained by regulating intake, intestinal absorption, bone deposition and resorption, and renal excretion of phosphate. The central molecule in the control of phosphate excretion from the kidney is the sodium/phosphate cotransporter NPT1 (SLC17A1; MIM 182308), which is located in the renal proximal tubule. NPT1 uses the transmembrane electrochemical potential gradient of sodium to transport phosphate across the cell membrane. SLC17A4 is a similar sodium/phosphate cotransporter in the intestinal mucosa that plays an important role in the absorption of phosphate from the intestine (summary by Shibui et al., 1999 [PubMed 10319585]).[supplied by OMIM, Feb 2011]

Chromosome

6

Cytoband

p22.2

Chromosome location (bp)

25754699 - 25781191

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000146039 (version 78.38)

Entrez gene

10050

UniProt

Q9Y2C5 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9Y2C5

Antibodypedia

SLC17A4 antibodies
 

PROTEIN VIEW

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SLC17A4-001
 
SLC17A4-201
 
SLC17A4-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC17A4-001 ENSP00000367137
ENST00000377905
Q9Y2C5
Show all »
Show » Show » 497 54.1 No >9
SLC17A4-201 ENSP00000380266
ENST00000397076
Q9Y2C5
Show all »
Show » Show » 221 24.2 No 5
SLC17A4-202 ENSP00000391345
ENST00000439485
Q9Y2C5
Show all »
Show » Show » 443 48.3 No >9