DOK2

GENE INFORMATION

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Gene name

DOK2 (HGNC Symbol)

Synonyms

Dok-2, p56dok-2

Description

Docking protein 2, 56kDa (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

p21.3

Chromosome location (bp)

21908873 - 21913860

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147443 (version 78.38)

Entrez gene

9046

UniProt

O60496 (UniProt - Evidence at protein level)

neXtProt

NX_O60496

Antibodypedia

DOK2 antibodies
 

PROTEIN VIEW

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DOK2-001
 
DOK2-004
 
DOK2-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DOK2-001 ENSP00000276420
ENST00000276420
O60496
Show all »
Show » Show » 412 45.4 No 0
DOK2-004 ENSP00000429224
ENST00000523932
E5RJ11
Show all »
Show » Show » 233 26 No 0
DOK2-007 ENSP00000430729
ENST00000518197
E5RIG9
Show all »
Show » Show » 151 16.7 No 0