MRPS28

GENE INFORMATION

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Gene name

MRPS28 (HGNC Symbol)

Synonyms

HSPC007, MRP-S28, MRPS35

Description

Mitochondrial ribosomal protein S28 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has been called mitochondrial ribosomal protein S35 in the literature. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q21.13

Chromosome location (bp)

79918717 - 80030289

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147586 (version 78.38)

Entrez gene

28957

UniProt

Q9Y2Q9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y2Q9

Antibodypedia

MRPS28 antibodies
 

PROTEIN VIEW

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MRPS28-001
 
MRPS28-002
 
MRPS28-007
 
MRPS28-008
 
MRPS28-009
 
MRPS28-010
 
MRPS28-011
 
MRPS28-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS28-001 ENSP00000276585
ENST00000276585
Q9Y2Q9
Show all »
Show » Show » 187 20.8 No 0
MRPS28-002 ENSP00000476135
ENST00000518371
Show » 83 9.6 No 0
MRPS28-007 ENSP00000427965
ENST00000521605
E5RFT8
Show all »
Show » 86 9.4 No 0
MRPS28-008 ENSP00000428744
ENST00000519120
E5RGC7
Show all »
Show » 103 11.7 No 0
MRPS28-009 ENSP00000430401
ENST00000520946
E5RK86
Show all »
Show » 109 12.4 Yes 0
MRPS28-010 ENSP00000428880
ENST00000521434
E5RFH3
Show all »
Show » 125 14.3 Yes 0
MRPS28-011 ENSP00000428050
ENST00000519386
E5RGC7
Show all »
Show » 143 15.8 No 0
MRPS28-012 ENSP00000427846
ENST00000518271
Show » 163 18.2 No 0