RPL7

GENE INFORMATION

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Gene name

RPL7 (HGNC Symbol)

Synonyms

humL7-1, L7

Description

Ribosomal protein L7 (HGNC Symbol)

Entrez gene summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q21.11

Chromosome location (bp)

73290267 - 73295789

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147604 (version 78.38)

Entrez gene

6129

UniProt

P18124 (UniProt - Evidence at protein level)

neXtProt

NX_P18124

Antibodypedia

RPL7 antibodies
 

PROTEIN VIEW

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RPL7-001
 
RPL7-002
 
RPL7-003
 
RPL7-004
 
RPL7-005
 
RPL7-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPL7-001 ENSP00000339795
ENST00000352983
P18124
Show all »
Show » Show » 248 29.2 No 0
RPL7-002 ENSP00000379731
ENST00000396467
A8MUD9
Show all »
Show » 208 24.4 No 0
RPL7-003 ENSP00000379729
ENST00000396465
A8MUD9
Show all »
Show » 208 24.4 No 0
RPL7-004 ENSP00000379730
ENST00000396466
A8MUD9
Show all »
Show » 208 24.4 No 0
RPL7-005 ENSP00000401300
ENST00000431653
C9JZ88
Show all »
Show » 88 10.6 No 0
RPL7-006 ENSP00000415808
ENST00000435330
C9JIJ5
Show all »
Show » 99 11.9 No 0