PLIN2

GENE INFORMATION

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Gene name

PLIN2 (HGNC Symbol)

Synonyms

ADFP, ADRP

Description

Perilipin 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]

Chromosome

9

Cytoband

p22.1

Chromosome location (bp)

19108375 - 19149290

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147872 (version 78.38)

Entrez gene

123

UniProt

Q99541 (UniProt - Evidence at protein level)

neXtProt

NX_Q99541

Antibodypedia

PLIN2 antibodies
 

PROTEIN VIEW

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PLIN2-002
 
PLIN2-003
 
PLIN2-005
 
PLIN2-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PLIN2-002 ENSP00000369832
ENST00000380465
Q5SYF4
Show all »
Show » 126 13.7 No 0
PLIN2-003 ENSP00000369831
ENST00000380464
Q5SYF3
Show all »
Show » 110 11.9 No 0
PLIN2-005 ENSP00000403421
ENST00000434144
Q5SYF5
Show all »
Show » 125 13.2 No 0
PLIN2-007 ENSP00000276914
ENST00000276914
Q99541
Show all »
Show » Show » 437 48.1 No 0