ARID5B

GENE INFORMATION

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Gene name

ARID5B (HGNC Symbol)

Synonyms

FLJ21150, MRF2

Description

AT rich interactive domain 5B (MRF1-like) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Chromosome

10

Cytoband

q21.2

Chromosome location (bp)

61901300 - 62096944

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000150347 (version 78.38)

Entrez gene

84159

UniProt

Q14865 (UniProt - Evidence at protein level)

neXtProt

NX_Q14865

Antibodypedia

ARID5B antibodies
 

PROTEIN VIEW

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ARID5B-001
 
ARID5B-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARID5B-001 ENSP00000279873
ENST00000279873
Q14865
Show all »
Show » Show » 1188 132.4 No 0
ARID5B-002 ENSP00000308862
ENST00000309334
Q14865
Show all »
Show » Show » 945 104.6 No 0