CD226

GENE INFORMATION

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Gene name

CD226 (HGNC Symbol)

Synonyms

DNAM-1, DNAM1, PTA1, TLiSA1

Description

CD226 molecule (HGNC Symbol)

Entrez gene summary

This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Chromosome

18

Cytoband

q22.2

Chromosome location (bp)

69831158 - 69961803

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000150637 (version 78.38)

Entrez gene

10666

UniProt

Q15762 (UniProt - Evidence at protein level)

neXtProt

NX_Q15762

Antibodypedia

CD226 antibodies
 

PROTEIN VIEW

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CD226-001
 
CD226-003
 
CD226-004
 
CD226-005
 
CD226-006
 
CD226-007
 
CD226-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD226-001 ENSP00000280200
ENST00000280200
Q15762
Show all »
Show » Show » 336 38.6 Yes 1
CD226-003 ENSP00000464084
ENST00000581982
J3QR77
Show all »
Show » 181 21.1 No 1
CD226-004 ENSP00000461947
ENST00000582621
Q15762
Show all »
Show » Show » 336 38.6 Yes 1
CD226-005 ENSP00000463335
ENST00000580335
J3QL19
Show all »
Show » Show » 127 14.6 Yes 0
CD226-006 ENSP00000464334
ENST00000583955
J3QRQ4
Show all »
Show » Show » 132 15.2 Yes 0
CD226-007 ENSP00000462453
ENST00000577287
J3QR77
Show all »
Show » 181 21.1 No 1
CD226-009 ENSP00000463927
ENST00000579496
J3QQW1
Show all »
Show » Show » 276 31.3 Yes 1