EIF4E

GENE INFORMATION

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Gene name

EIF4E (HGNC Symbol)

Synonyms

EIF4E1, EIF4EL1, EIF4F

Description

Eukaryotic translation initiation factor 4E (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of cellular mRNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the mRNA. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Chromosome

4

Cytoband

q23

Chromosome location (bp)

98871684 - 98930637

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000151247 (version 78.38)

Entrez gene

1977

UniProt

P06730 (UniProt - Evidence at protein level)

neXtProt

NX_P06730

Antibodypedia

EIF4E antibodies
 

PROTEIN VIEW

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EIF4E-001
 
EIF4E-002
 
EIF4E-005
 
EIF4E-007
 
EIF4E-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EIF4E-001 ENSP00000389624
ENST00000450253
P06730
Show all »
Show » Show » 217 25.1 No 0
EIF4E-002 ENSP00000280892
ENST00000280892
P06730
Show all »
Show » Show » 237 27.3 No 0
EIF4E-005 ENSP00000423977
ENST00000504432
D6RBW1
Show all »
Show » Show » 245 28.5 No 0
EIF4E-007 ENSP00000425561
ENST00000505992
P06730
Show all »
Show » Show » 248 28.8 No 0
EIF4E-008 ENSP00000421287
ENST00000511644
Show » Show » 155 18.4 No 0