ITIH2

GENE INFORMATION

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Gene name

ITIH2 (HGNC Symbol)

Synonyms

H2P

Description

Inter-alpha-trypsin inhibitor heavy chain 2 (HGNC Symbol)

Entrez gene summary

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322]; Himmelfarb et al., 2004 [PubMed 14744536]).[supplied by OMIM, Nov 2009]

Chromosome

10

Cytoband

p14

Chromosome location (bp)

7703269 - 7749520

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000151655 (version 78.38)

Entrez gene

3698

UniProt

P19823 (UniProt - Evidence at protein level)

neXtProt

NX_P19823

Antibodypedia

ITIH2 antibodies
 

PROTEIN VIEW

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ITIH2-001
 
ITIH2-002
 
ITIH2-005
 
ITIH2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ITIH2-001 ENSP00000351190
ENST00000358415
P19823
Show all »
Show » Show » 946 106.5 Yes 0
ITIH2-002 ENSP00000368906
ENST00000379587
Q5T985
Show all »
Show » Show » 935 105.2 Yes 0
ITIH2-005 ENSP00000388826
ENST00000429820
Q5T987
Show all »
Show » 237 26.8 Yes 0
ITIH2-201 ENSP00000477794
ENST00000613369
Show » Show » 945 106.7 Yes 0