CENPU

GENE INFORMATION

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Gene name

CENPU (HGNC Symbol)

Synonyms

CENP-50, CENP-U, KLIP1, MLF1IP, PBIP1

Description

Centromere protein U (HGNC Symbol)

Entrez gene summary

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]

Chromosome

4

Cytoband

q35.1

Chromosome location (bp)

184694618 - 184734133

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000151725 (version 78.38)

Entrez gene

79682

UniProt

Q71F23 (UniProt - Evidence at protein level)

neXtProt

NX_Q71F23

Antibodypedia

CENPU antibodies
 

PROTEIN VIEW

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CENPU-001
 
CENPU-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CENPU-001 ENSP00000281453
ENST00000281453
Q71F23
Show all »
Show » Show » 418 47.5 No 0
CENPU-004 ENSP00000423167
ENST00000514781
D6R9S4
Show all »
Show » Show » 177 19.4 No 0