GGPS1

GENE INFORMATION

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Gene name

GGPS1 (HGNC Symbol)

Synonyms

GGPPS1

Description

Geranylgeranyl diphosphate synthase 1 (HGNC Symbol)

Entrez gene summary

This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010]

Chromosome

1

Cytoband

q42.3

Chromosome location (bp)

235327350 - 235344532

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000152904 (version 78.38)

Entrez gene

9453

UniProt

O95749 (UniProt - Evidence at protein level)

neXtProt

NX_O95749

Antibodypedia

GGPS1 antibodies
 

PROTEIN VIEW

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GGPS1-001
 
GGPS1-002
 
GGPS1-003
 
GGPS1-005
 
GGPS1-008
 
GGPS1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GGPS1-001 ENSP00000282841
ENST00000282841
O95749
Show all »
Show » Show » 300 34.9 No 0
GGPS1-002 ENSP00000375728
ENST00000391855
O95749
Show all »
Show » Show » 246 28.4 No 0
GGPS1-003 ENSP00000418690
ENST00000488594
O95749
Show all »
Show » Show » 300 34.9 No 0
GGPS1-005 ENSP00000417772
ENST00000471812
C9J7M1
Show all »
Show » Show » 242 28.1 No 0
GGPS1-008 ENSP00000417865
ENST00000497327
C9J6G3
Show all »
Show » Show » 230 26.6 No 0
GGPS1-201 ENSP00000351852
ENST00000358966
O95749
Show all »
Show » Show » 300 34.9 No 0