TMPRSS11D

GENE INFORMATION

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Gene name

TMPRSS11D

Synonyms

Description

Transmembrane protease, serine 11D (HGNC Symbol)

Entrez gene summary

This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq, Jul 2008]

Chromosome

4

Cytoband

q13.2

Chromosome location (bp)

67820876 - 67884032

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000153802 (version 78.38)

Entrez gene

9407

UniProt

O60235 (UniProt - Evidence at protein level)

neXtProt

NX_O60235

Antibodypedia

TMPRSS11D antibodies
 

PROTEIN VIEW

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TMPRSS11D-001
 
TMPRSS11D-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TMPRSS11D-001 ENSP00000283916
ENST00000283916
O60235
Show all »
Show » Show » 418 46.3 No 1
TMPRSS11D-007 ENSP00000421381
ENST00000514868
Show » 65 7.1 No 0