NEIL2

GENE INFORMATION

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Gene name

NEIL2 (HGNC Symbol)

Synonyms

FLJ31644, MGC2832, MGC4505, NEH2

Description

Nei endonuclease VIII-like 2 (E. coli) (HGNC Symbol)

Entrez gene summary

NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])[supplied by OMIM, Mar 2008]

Chromosome

8

Cytoband

p23.1

Chromosome location (bp)

11769639 - 11787346

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000154328 (version 78.38)

Entrez gene

252969

UniProt

Q969S2 (UniProt - Evidence at protein level)

neXtProt

NX_Q969S2

Antibodypedia

NEIL2 antibodies
 

PROTEIN VIEW

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NEIL2-001
 
NEIL2-002
 
NEIL2-003
 
NEIL2-004
 
NEIL2-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NEIL2-001 ENSP00000284503
ENST00000284503
Q969S2
Show all »
Show » Show » 332 36.8 No 0
NEIL2-002 ENSP00000435657
ENST00000528323
Q969S2
Show all »
Show » Show » 216 24.1 No 0
NEIL2-003 ENSP00000397538
ENST00000455213
Q969S2
Show all »
Show » Show » 332 36.8 No 0
NEIL2-004 ENSP00000394023
ENST00000436750
Q969S2
Show all »
Show » Show » 332 36.8 No 0
NEIL2-007 ENSP00000384070
ENST00000403422
Q969S2
Show all »
Show » Show » 271 29.9 No 0