PPP4R1

GENE INFORMATION

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Gene name

PPP4R1 (HGNC Symbol)

Synonyms

PP4R1

Description

Protein phosphatase 4, regulatory subunit 1 (HGNC Symbol)

Entrez gene summary

This gene encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

Chromosome

18

Cytoband

p11.22

Chromosome location (bp)

9546791 - 9615240

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000154845 (version 78.38)

Entrez gene

9989

UniProt

Q8TF05 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TF05

Antibodypedia

PPP4R1 antibodies
 

PROTEIN VIEW

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PPP4R1-001
 
PPP4R1-002
 
PPP4R1-006
 
PPP4R1-007
 
PPP4R1-008
 
PPP4R1-011
 
PPP4R1-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPP4R1-001 ENSP00000383402
ENST00000400556
Q8TF05
Show all »
Show » Show » 950 107 No 0
PPP4R1-002 ENSP00000383401
ENST00000400555
Q8TF05
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Show » Show » 933 105.2 No 0
PPP4R1-006 ENSP00000463345
ENST00000580745
J3QL26
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Show » Show » 135 15.5 No 0
PPP4R1-007 ENSP00000463909
ENST00000582240
J3QQV0
Show all »
Show » Show » 190 21 No 0
PPP4R1-008 ENSP00000463459
ENST00000584074
J3QLA6
Show all »
Show » Show » 151 17.2 No 0
PPP4R1-011 ENSP00000462399
ENST00000581250
J3KSB0
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Show » Show » 143 16.3 No 0
PPP4R1-012 ENSP00000462161
ENST00000581835
J3KRU1
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Show » Show » 97 11.2 No 0