RHOC

GENE INFORMATION

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Gene name

RHOC (HGNC Symbol)

Synonyms

ARH9, ARHC, RhoC

Description

Ras homolog family member C (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p13.2

Chromosome location (bp)

112701106 - 112707434

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000155366 (version 78.38)

Entrez gene

389

UniProt

P08134 (UniProt - Evidence at protein level)

neXtProt

NX_P08134

Antibodypedia

RHOC antibodies
 

PROTEIN VIEW

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 « 
 
RHOC-001
 
RHOC-002
 
RHOC-003
 
RHOC-004
 
RHOC-005
 
RHOC-006
 
RHOC-008
 
RHOC-009
 
RHOC-010
 
RHOC-012
 
RHOC-013
 
RHOC-018
 
RHOC-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RHOC-001 ENSP00000345236
ENST00000339083
P08134
Show all »
Show » Show » 193 22 No 0
RHOC-002 ENSP00000285735
ENST00000285735
P08134
Show all »
Show » Show » 193 22 No 0
RHOC-003 ENSP00000358656
ENST00000369642
P08134
Show all »
Show » Show » 193 22 No 0
RHOC-004 ENSP00000358651
ENST00000369637
P08134
Show all »
Show » Show » 193 22 No 0
RHOC-005 ENSP00000358650
ENST00000369636
Q5JR05
Show all »
Show » Show » 199 22 No 0
RHOC-006 ENSP00000434877
ENST00000484054
E9PN11
Show all »
Show » Show » 129 13.9 No 0
RHOC-008 ENSP00000390823
ENST00000425265
Q5JR08
Show all »
Show » Show » 189 21.6 No 0
RHOC-009 ENSP00000358646
ENST00000369632
P08134
Show all »
Show » Show » 193 22 No 0
RHOC-010 ENSP00000399424
ENST00000436685
Q5JR07
Show all »
Show » Show » 127 14.4 No 0
RHOC-012 ENSP00000358652
ENST00000369638
P08134
Show all »
Show » Show » 193 22 No 0
RHOC-013 ENSP00000395791
ENST00000414971
Q5JR06
Show all »
Show » Show » 92 10.3 No 0
RHOC-018 ENSP00000436240
ENST00000534717
E9PQH6
Show all »
Show » Show » 169 19.2 No 0
RHOC-201 ENSP00000358647
ENST00000369633
P08134
Show all »
Show » Show » 193 22 No 0