RASA2

GENE INFORMATION

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Gene name

RASA2 (HGNC Symbol)

Synonyms

GAP1M

Description

RAS p21 protein activator 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Chromosome

3

Cytoband

q23

Chromosome location (bp)

141487047 - 141615342

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000155903 (version 78.38)

Entrez gene

5922

UniProt

Q15283 (UniProt - Evidence at protein level)

neXtProt

NX_Q15283

Antibodypedia

RASA2 antibodies
 

PROTEIN VIEW

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RASA2-001
 
RASA2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RASA2-001 ENSP00000286364
ENST00000286364
Q15283
Show all »
Show » Show » 849 96.5 Yes 0
RASA2-201 ENSP00000391677
ENST00000452898
Show » Show » 853 97 Yes 0