MMP16

GENE INFORMATION

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Gene name

MMP16 (HGNC Symbol)

Synonyms

C8orf57, DKFZp761D112, MT3-MMP

Description

Matrix metallopeptidase 16 (membrane-inserted) (HGNC Symbol)

Entrez gene summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq, Oct 2010]

Chromosome

8

Cytoband

q21.3

Chromosome location (bp)

88032009 - 88328025

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000156103 (version 78.38)

Entrez gene

4325

UniProt

P51512 (UniProt - Evidence at protein level)

neXtProt

NX_P51512

Antibodypedia

MMP16 antibodies
 

PROTEIN VIEW

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MMP16-001
 
MMP16-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MMP16-001 ENSP00000286614
ENST00000286614
P51512
Show all »
Show » Show » 607 69.5 Yes 1
MMP16-004 ENSP00000429147
ENST00000522726
E5RJA7
Show all »
Show » Show » 168 19.5 No 0