DCK

GENE INFORMATION

? »

Gene name

DCK

Synonyms

Description

Deoxycytidine kinase (HGNC Symbol)

Entrez gene summary

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008]

Chromosome

4

Cytoband

q13.3

Chromosome location (bp)

70992538 - 71030914

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000156136 (version 78.38)

Entrez gene

1633

UniProt

P27707 (UniProt - Evidence at protein level)

neXtProt

NX_P27707

Antibodypedia

DCK antibodies
 

PROTEIN VIEW

? »
 
 
 
DCK-001
 
DCK-004
 
DCK-005
 
DCK-006
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DCK-001 ENSP00000286648
ENST00000286648
P27707
Show all »
Show » Show » 260 30.5 No 0
DCK-004 ENSP00000425578
ENST00000504730
D6RCP9
Show all »
Show » Show » 199 22.9 No 0
DCK-005 ENSP00000421508
ENST00000504952
D6RFG8
Show all »
Show » Show » 317 36.8 No 0
DCK-006 ENSP00000422971
ENST00000509617
Show » 15 1.6 No 0